DL-Ethionine , 98% , 67-21-0

Synonym(s):
DL-2-Amino-4-(ethylthio)butyric acid

Update time: 2022-07-08

Melting point:	265-268 °C
alpha	[α]D20 0±0.5° (c=5, dil. HCl)
Boiling point:	310℃
Density	1.164
refractive index	1.5500 (estimate)
Flash point:	142℃
storage temp.	-20°C
solubility	Methanol (Slightly, Heated), Water (Slightly)
pka	2.23±0.10(Predicted)
form	Crystalline Powder or Flakes
color	White to off-white
Water Solubility	Soluble in water.
Merck	14,3738
BRN	1722529
Major Application	cell analysis
InChI	1S/C6H13NO2S/c1-2-10-4-3-5(7)6(8)9/h5H,2-4,7H2,1H3,(H,8,9)
InChIKey	GGLZPLKKBSSKCX-UHFFFAOYSA-N
SMILES	CCSCCC(N)C(O)=O
CAS DataBase Reference	67-21-0(CAS DataBase Reference)
EPA Substance Registry System	S-Ethylhomocysteine (67-21-0)

antineoplastic; inhibitor DNA methylation

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319-H335
Precautionary statements	P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs	Respiratory system
PPE	dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26
WGK Germany	3
RTECS	ES6825200
TSCA	TSCA listed
HS Code	29309090
Storage Class	11 - Combustible Solids
Hazard Classifications	Eye Irrit. 2 Skin Irrit. 2 STOT SE 3
Toxicity	The Sethyl analog of methionine. It is a carcinogen and hepatotoxic agent once proposed as an antineoplastic agent. It inhibits the incorporation of methionine and glycine into proteins and substitutes for methionine in transmethylation reactions, the ethyl group appearing in the products in place of the methyl groups of methionine (e.g., ethylcholine is formed instead of choline). Ethionine is currently used only as an experimental compound in studies of hepatotoxicity and methionine metabolism and nutrition.