Ethinyl Estradiol , ≥98% , 57-63-6
Synonym(s):
17α-Ethynyl-1,3,5(10)-estratriene-3,17β-diol;17α-Ethynylestradiol;19-Nor-1,3,5(10),17α-pregnatrien-20-yne-3,17-diol;EE;Ethinylestradiol
CAS NO.：57-63-6
Empirical Formula: C20H24O2
Molecular Weight: 296.41
MDL number: MFCD00003690
EINECS: 200-342-2
| Pack Size | Price | Stock | Quantity |
| 1G | RMB96.80 | In Stock |
|
| 5G | RMB331.20 | In Stock |
|
| 25G | RMB1276.00 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 182-183 °C(lit.) |
| Boiling point: | 378°C (rough estimate) |
| Density | 1.0944 (rough estimate) |
| refractive index | -30 ° (C=0.4, Pyridine) |
| Flash point: | 9℃ |
| storage temp. | room temp |
| solubility | ethanol: 50 mg/mL, clear, slightly yellow |
| form | Solid |
| pka | pKa 10.32 (Uncertain) |
| color | White to Light yellow to Light orange |
| biological source | synthetic |
| Merck | 14,3734 |
| BRN | 2419975 |
| BCS Class | 3/1 |
| InChIKey | BFPYWIDHMRZLRN-SLHNCBLASA-N |
| CAS DataBase Reference | 57-63-6(CAS DataBase Reference) |
| NIST Chemistry Reference | Ethinyl estradiol(57-63-6) |
| EPA Substance Registry System | Ethinyl estradiol (57-63-6) |
Description and Uses
Estrogens direct the development of the female genotype in embryogenesis and at puberty. Estradiol is the major estrogen secreted by the premenopausal ovary. Ethynyl estradiol is a synthetic analog of 17β-estradiol . A USP-approved grade of ethynyl estradiol is often formulated in combination with a progestin such as norgestrel /levonorgestrel or desogestrel and provided for use as an oral contraceptive. Efficacy of oral administration of ethynyl estradiol is facilitated by the ethynyl substitution at the C-17 position, which inhibits first pass hepatic metabolism. Ethynyl estradiol is also rapidly and almost completely absorbed from the gastrointestinal tract.
estrogen, plus progestogen as oral contraceptive
Safety
| Symbol(GHS) |    GHS07,GHS08,GHS09 |
| Signal word | Danger |
| Hazard statements | H302-H350-H410 |
| Precautionary statements | P202-P264-P270-P273-P301+P312-P308+P313 |
| Hazard Codes | T,F |
| Risk Statements | 45-22-39/23/24/25-23/24/25-11 |
| Safety Statements | 53-36/37/39-45-36/37-16 |
| RIDADR | UN1230 - class 3 - PG 2 - Methanol, solution |
| WGK Germany | 3 |
| RTECS | RC8925000 |
| F | 8 |
| HazardClass | 9 |
| HS Code | 29372390 |
| Hazardous Substances Data | 57-63-6(Hazardous Substances Data) |
| Toxicity | LD50 oral in rat: 960mg/kg |
| Limited Quantities | 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid) |
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) |
