Z-Pro-OH , 98% , 1148-11-4

Synonym(s):
Z-L-Proline

CAS NO.：1148-11-4

Empirical Formula: C13H15NO4

Molecular Weight: 249.26

MDL number: MFCD00003170

EINECS: 214-557-4

PRODUCT Properties

• Melting point: 75-77 °C
• alpha: -60 º (c=2,AcOH)
• Boiling point: 392.36°C (rough estimate)
• Density: 1.1952 (rough estimate)
• refractive index: -40 ° (C=2, EtOH)
• storage temp.: Sealed in dry,Room Temperature
• solubility: Solubility in methanol, almost transparency.
• pka: 3.99±0.20(Predicted)
• form: Crystalline Powder or Crystals
• color: White to off-white
• optical activity: [α]20/D 42°, c = 2 in ethanol
• BRN: 88579
• InChI: InChI=1S/C13H15NO4/c15-12(16)11-7-4-8-14(11)13(17)18-9-10-5-2-1-3-6-10/h1-3,5-6,11H,4,7-9H2,(H,15,16)/t11-/m0/s1
• InChIKey: JXGVXCZADZNAMJ-NSHDSACASA-N
• SMILES: N1(C(OCC2=CC=CC=C2)=O)CCC[C@H]1C(O)=O
• CAS DataBase Reference: 1148-11-4(CAS DataBase Reference)

Description and Uses

N-(Benzyloxycarbonyl)-L-proline is a potent in vitro and in vivo inhibitor of prolidase; a specific peptidase that cleaves dipeptides with a C-terminal prolyl and hydroxylprolyl residue. It is also used in the synthesis of N-(L-Prolyl)-β-alanine which is a derivative of the naturally occurring beta amino acid β-Alanine.

Safety

• Symbol(GHS): GHS05
• Signal word: Danger
• Hazard statements: H318
• Precautionary statements: P271-P261-P280
• Hazard Codes: Xn
• Risk Statements: 62-36/37/38-20/21/22
• Safety Statements: 22-24/25-36-26
• WGK Germany: 3
• RTECS: UY0745000
• HazardClass: IRRITANT
• HS Code: 29339900