4-((5,6-Diphenylpyrazin-2-yl)(isopropyl)amino)butan-1-ol , 98% , 475086-75-0

CAS NO.：475086-75-0

Empirical Formula: C23H27N3O

Molecular Weight: 361.48

MDL number:

EINECS: 813-799-3

PRODUCT Properties

• Melting point: 68 - 71°C
• Boiling point: 514.4±50.0 °C(Predicted)
• Density: 1.112±0.06 g/cm3(Predicted)
• storage temp.: Sealed in dry,Room Temperature
• solubility: Chloroform (Slightly), DMSO (Slightly)
• pka: 15.05±0.10(Predicted)
• form: Solid
• color: Pale Yellow to Light Yellow
• InChI: InChI=1S/C23H27N3O/c1-18(2)26(15-9-10-16-27)21-17-24-22(19-11-5-3-6-12-19)23(25-21)20-13-7-4-8-14-20/h3-8,11-14,17-18,27H,9-10,15-16H2,1-2H3
• InChIKey: PKBSUZWFQXNCSI-UHFFFAOYSA-N
• SMILES: C(O)CCCN(C1=NC(C2=CC=CC=C2)=C(C2=CC=CC=C2)N=C1)C(C)C

Description and Uses

4-[(5,6-Diphenyl-2-pyrazinyl)(1-methylethyl)amino]-1-butanol is a diphenylpyrazine derivative which belongs to a class of prostacyclin receptor agonists. It is an impurity of Selexipag (S253150) that is a potential drug for the treatment of various vascular disorders such as pulmonary arterial hypertension and arteriosclerosis obliterans.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319-H335
• Precautionary statements: P261-P280-P301+P312-P302+P352-P305+P351+P338