(2-Ethoxy-2-oxoethyl)triphenylphosphoniumchloride , 97% , 17577-28-5

Synonym(s):
(2-Ethoxy-2-oxoethyl)triphenylphosphonium chloride

CAS NO.：17577-28-5

Empirical Formula: C22H22O2P.Cl

Molecular Weight: 384.84

MDL number: MFCD03791276

EINECS: 241-548-2

PRODUCT Properties

• Melting point: 120-123 °C (dec.) 120-123 °C (lit.)
• storage temp.: 2-8°C
• Appearance: White to off-white Solid
• Sensitive: Hygroscopic
• BRN: 3924139
• InChI: 1S/C22H22O2P.ClH/c1-2-24-22(23)18-25(19-12-6-3-7-13-19,20-14-8-4-9-15-20)21-16-10-5-11-17-21;/h3-17H,2,18H2,1H3;1H/q+1;/p-1
• InChIKey: DJGHVEPNEJKZBF-UHFFFAOYSA-M
• SMILES: [Cl-].CCOC(=O)C[P+](c1ccccc1)(c2ccccc2)c3ccccc3
• CAS DataBase Reference: 17577-28-5(CAS DataBase Reference)
• EPA Substance Registry System: Phosphonium, (2-ethoxy-2-oxoethyl)triphenyl-, chloride (17577-28-5)

Description and Uses

Reactant for:

• Preparation of disubstituted tetrahydrofurans as selective serotonin re-uptake inhibitors for the treatment of depression
• Ring-opening reactions with Wittig reagents
• Enantioselective total synthesis of the phytotoxic lactone herbarumin III via Keck′s asymmetric allylation and Sharpless epoxidation
• Synthesis of fluorobenzofurans via microwave-assisted tandem intramolecular Wittig and Claisen rearrangement reactions
• Preparation of phosphonium derivatives of coumarin

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P305+P351+P338
• target organs: Respiratory system
• PPE: dust mask type N95 (US), Eyeshields, Gloves
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• F: 9
• TSCA: TSCA listed
• HS Code: 29319019
• Storage Class: 11 - Combustible Solids
• Hazard Classifications: Eye Irrit. 2; Skin Irrit. 2; STOT SE 3