(2S,4R)-1-tert-Butyl2-methyl4-fluoropyrrolidine-1,2-dicarboxylate , 97% , 203866-18-6

Synonym(s):
1-tert-Butyl 2-methyl (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate

CAS NO.：203866-18-6

Empirical Formula: C11H18FNO4

Molecular Weight: 247.26

MDL number: MFCD07367993

PRODUCT Properties

• Melting point: 34-39 °C
• Density: 1.16
• Flash point: 110 °C
• storage temp.: 2-8°C
• form: powder
• Appearance: Colorless to off-white <36°C Solid,>39°C Liquid
• optical activity: [α]22/D -80.0°, c = 1 in methanol
• Water Solubility: Insoluble in water.
• InChI: InChI=1S/C11H18FNO4/c1-11(2,3)17-10(15)13-6-7(12)5-8(13)9(14)16-4/h7-8H,5-6H2,1-4H3/t7-,8+/m1/s1
• InChIKey: METPQQHVRNLTRX-SFYZADRCSA-N
• SMILES: N1(C(OC(C)(C)C)=O)C[C@H](F)C[C@H]1C(OC)=O

Description and Uses

N-Boc-trans-4-fluoro-L-proline methyl ester is used to prepare (S)-2-[N-(N'-benzyl-(S)-4-fluoro-L-prolyl)amino]benzophenone by reacting with of 2-aminobenzophenone in the presence of potassium tert -butoxide.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319
• Precautionary statements: P264b-P270-P280-P301+P312-P302+P352-P305+P351+P338-P330-P332+P313-P337+P313-P362+P364-P403-P501c
• WGK Germany: 3
• HS Code: 2933998090