1-Boc-3-(4-Bromophenyl)piperidine , 95+% , 769944-73-2

CAS NO.：769944-73-2

Empirical Formula: C16H22BrNO2

Molecular Weight: 340.26

MDL number:

PRODUCT Properties

• Boiling point: 398.5±42.0 °C(Predicted)
• Density: 1.283
• storage temp.: 2-8°C
• pka: -1.84±0.40(Predicted)
• InChI: InChI=1S/C16H22BrNO2/c1-16(2,3)20-15(19)18-10-4-5-13(11-18)12-6-8-14(17)9-7-12/h6-9,13H,4-5,10-11H2,1-3H3
• InChIKey: WRSHWNCUNYWQBB-UHFFFAOYSA-N
• SMILES: N1(C(OC(C)(C)C)=O)CCCC(C2=CC=C(Br)C=C2)C1

Description and Uses

tert-Butyl 3-(4-Bromophenyl)piperidine-1-carboxylate is an intermediate of Niraparib (N481400), a novel oral poly(ADP-ribose)polymerase (PARP) inhibitor efficacious in BRCA-1 and -2 mutant tumors.

Safety

• Symbol(GHS): GHS05
• Signal word: Danger
• Hazard statements: H318
• Precautionary statements: P280-P305+P351+P338+P310
• HS Code: 2933399990