LN-779127
GRAYANOTOXIN III , 98%+ , 4678-45-9
Update time: 2023-04-23
PRODUCT Properties
| Melting point: | 218 °C (decomp) |
| Boiling point: | 552.6±50.0 °C(Predicted) |
| Density | 1.36±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | Acetonitrile: Slightly Soluble: 0.1-1 mg/ml Water: Slightly Soluble: 0.1-1 mg/ml |
| pka | 13.79±0.70(Predicted) |
Description and Uses
Grayanotoxin III (GTX-III) is a diterpene toxin that has been found in R. ponticum nectar, a component of mad honey.1 In vivo, GTX-III (0.1 and 0.25 mg/kg) induces salivation, emesis, and hind paw paralysis in mice.2 It is lethal to mice (LD50 = 0.84 mg/kg).WARNING This product is not for human or veterinary use.
Safety
| Symbol(GHS) |  GHS06 |
| Signal word | Danger |
| Hazard statements | H301-H315-H319-H331-H311 |
| Precautionary statements | P264-P270-P301+P310-P321-P330-P405-P501-P264-P280-P305+P351+P338-P337+P313P-P280-P302+P352-P312-P322-P361-P363-P405-P501-P264-P280-P302+P352-P321-P332+P313-P362-P261-P271-P304+P340-P311-P321-P403+P233-P405-P501 |
| Hazard Codes | T |
| Risk Statements | 23/24/25-36/38 |
| Safety Statements | 22-26-36/37/39-45 |
| RIDADR | UN 2811 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | PB9190000 |
| HazardClass | 6.1(a) |
| PackingGroup | I |
| Toxicity | LD50 i.p. in mice: 0.84 mg/kg (Hikino, 1976) |
