M5271935
RG7440 , 99% , 1001264-89-6
| Pack Size | Price | Stock | Quantity |
| 1mg | RMB422.40 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | >106°C (dec.) |
| Boiling point: | 669.4±55.0 °C(Predicted) |
| Density | 1.254 |
| storage temp. | Hygroscopic, Refrigerator, under inert atmosphere |
| solubility | Soluble in DMSO. |
| pka | 13.11±0.40(Predicted) |
| form | Solid |
| color | peachy |
Description and Uses
(2S)-2-(4-Chlorophenyl)-1-[4-[(5R,7R)-6,7-dihydro-7-hydroxy-5-methyl-5H-cyclopentapyrimidin-4-yl]-1-piperazinyl]-3-[(1-methylethyl)amino]-1-propanone is a highly selective AKT inhibitor targeting Akt1, Akt2 and Akt3. Studies have shown its use in combination with vemurafenib (V118500), have demonstrated therapeutic value in the treatment of hyperproliferative disorders such as cancer.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a |
