PRODUCT Properties
| Melting point: | 177-177.5 °C |
| Boiling point: | 508.4±50.0 °C(Predicted) |
| Density | 1.296±0.06 g/cm3(Predicted) |
| solubility | DMSO: 2 mg/mL, clear (warmed) |
| form | powder |
| pka | 7.29±0.20(Predicted) |
| color | white to beige |
| SMILES | O=C1C2=C(C=C(C(OC)=C2O)OC)N(C)C3=C1C=CC=C3 |
Description and Uses
Arborinine is a potent and orally activeLSD1 inhibitor. Arborinine increases the expression of H3K4me1/2, H3K9me1/2, E-cad protein and decreases the expression of UBE2O protein level. Arborinine induces cell cycle arrest at S phase. Arborinine shows antitumor activity [1][2].
