lyophilizedpowder,100-300 units/mgprotein(biuret) , 9015-68-3
Synonym(s):
L -Asparagine Amidohydrolase
CAS NO.：9015-68-3
Empirical Formula: C14H17NO4S
Molecular Weight: 295.35
MDL number: MFCD00130565
EINECS: 232-765-3
| Pack Size | Price | Stock | Quantity |
| 100UNITS | RMB2464.30 | In Stock |
|
| 1000UNITS | RMB11762.84 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| alpha | D20 -30 to -32° |
| storage temp. | 2-8°C |
| form | suspension |
| color | Crystals or powder |
| Merck | 13,841 |
| Specific Activity | 100-300units/mg protein (biuret) |
| CAS DataBase Reference | 9015-68-3 |
| EPA Substance Registry System | Asparaginase (9015-68-3) |
Description and Uses
Using the enzyme asparaginase (L-asparagine amidohydrolase, EC 3.5.1.1), it is
possible to significantly reduce the formation of the cooking carcinogen acrylamide
during roasting, deep-frying, or baking of foods. The enzyme hydrolyzes
free asparagine to aspartic acid, thereby preventing the formation of
acrylamide by reaction of asparagine with reducing sugars at elevated temperatures
during the Maillard reaction.
The mitigation of acrylamide formation is especially important for a number of
cereal- and potato-based products, including crackers, crispbread, gingerbread,
biscuits, French fries, and potato chips. After asparaginase pretreatment, the
acrylamide concentration of certain foods could be reduced by up to 97 % [84, 86].
By means of in vitro directed evolution, the properties of asparaginase were
optimized. For example, an Asp133Leu mutation of a wild-type enzyme showed a
significantly improved thermal stability. The enzyme’s half-life at 50 C increased
from 3 to 160 h, and the half-inactivation temperature of the mutant was 9 C
higher.
Antineoplastic.
Safety
| Symbol(GHS) |   GHS07,GHS08 |
| Signal word | Warning |
| Hazard statements | H317-H361 |
| Precautionary statements | P201-P280-P302+P352-P308+P313 |
| Hazard Codes | T,Xn |
| Risk Statements | 61-42/43-63 |
| Safety Statements | 53-22-36/37/39-45-36/37 |
| RIDADR | 3249 |
| WGK Germany | 3 |
| RTECS | CI9000000 |
| F | 10-21 |
| HazardClass | 6.1(a) |
| PackingGroup | II |
| HS Code | 3507909090 |
| Hazardous Substances Data | 9015-68-3(Hazardous Substances Data) |
| Toxicity | TDLo ims-chd: 8145 iu/kg/1W:SYS CANCAR 34,780,74 |
