PRODUCT Properties
| Boiling point: | 78-81 °C/8 mmHg (lit.) |
| Density | 0.893 g/mL at 25 °C (lit.) |
| refractive index | n |
| Flash point: | >230 °F |
| storage temp. | RT, stored under nitrogen |
| form | Liquid |
| Specific Gravity | 0.893 |
| color | Clear colorless |
| Water Solubility | Sparingly soluble in water. |
| Sensitive | Air & Moisture Sensitive |
| Hydrolytic Sensitivity | 8: reacts rapidly with moisture, water, protic solvents |
| BRN | 2043814 |
| InChI | InChI=1S/C9H27O3PSi3/c1-14(2,3)10-13(11-15(4,5)6)12-16(7,8)9/h1-9H3 |
| InChIKey | VMZOBROUFBEGAR-UHFFFAOYSA-N |
| SMILES | [Si](C)(C)(OP(O[Si](C)(C)C)O[Si](C)(C)C)C |
| CAS DataBase Reference | 1795-31-9(CAS DataBase Reference) |
Description and Uses
Tris(trimethylsilyl) Phosphite is used in the studies of bisphosphonic acids as effective inhibitor of glutamine synthetase, a promising approach for the discovery of novel drugs against tuberculosis. It also acts as a reagent in the preparation of substituted calix[4]arenes bearing one or two α-hydroxymethylphosphonic acid fragments at upper rim of macrocycle as inhibitors of glutathione S-transferase in vitro.
