Boc-β-Ala-OH , 98% , 3303-84-2

Synonym(s):
Boc-β-alanine

CAS NO.：3303-84-2

Empirical Formula: C8H15NO4

Molecular Weight: 189.21

MDL number: MFCD00037291

EINECS: 221-979-2

PRODUCT Properties

• Melting point: 76-78 °C
• Boiling point: 333.9±25.0 °C(Predicted)
• Density: 1.129±0.06 g/cm3(Predicted)
• storage temp.: Keep in dark place,Sealed in dry,Room Temperature
• solubility: DMSO (Slightly), Methanol (Slightly)
• pka: 4.46±0.10(Predicted)
• form: Crystalline Powder
• color: White to off-white
• BRN: 1909986
• InChI: InChI=1S/C8H15NO4/c1-8(2,3)13-7(12)9-5-4-6(10)11/h4-5H2,1-3H3,(H,9,12)(H,10,11)
• InChIKey: WCFJUSRQHZPVKY-UHFFFAOYSA-N
• SMILES: C(=O)(NCCC(=O)O)OC(C)(C)C
• CAS DataBase Reference: 3303-84-2(CAS DataBase Reference)

Description and Uses

Boc-beta-Ala-OH is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Boc-?β-?Ala-?OH is a reagent used in the synthesis of quinazolines as platelet aggregation inhibitors and ligands of integrin.

Safety

• Symbol(GHS): GHS07,GHS05
• Signal word: Danger
• Hazard statements: H319-H314-H335
• Precautionary statements: P264-P280-P305+P351+P338-P337+P313P-P260-P264-P280-P301+P330+P331-P303+P361+P353-P363-P304+P340-P310-P321-P305+P351+P338-P405-P501
• Hazard Codes: Xn
• Risk Statements: 20/21/22-36/37/38
• Safety Statements: 22-24/25-36-26
• WGK Germany: 3
• HazardClass: IRRITANT
• HS Code: 29241990