Bis(3,5-di-tert-butyl-4-methoxyphenyl)chlorophosphine , Null , 212713-08-1

Synonym(s):
Bis[3,5-bis(1,1-dimethylethyl)-4-methoxyphenyl]phosphinous chloride

CAS NO.：212713-08-1

Empirical Formula: C30H46ClO2P

Molecular Weight: 505.11

MDL number: MFCD08458881

EINECS: 633-650-4

PRODUCT Properties

• Melting point: 116-120 °C
• Boiling point: 552.5±50.0 °C(Predicted)
• form: solid
• Water Solubility: Reacts with water.
• Sensitive: Air & Moisture Sensitive
• InChI: 1S/C30H46ClO2P/c1-27(2,3)21-15-19(16-22(25(21)32-13)28(4,5)6)34(31)20-17-23(29(7,8)9)26(33-14)24(18-20)30(10,11)12/h15-18H,1-14H3
• InChIKey: VOGHMZHRQUWLRE-UHFFFAOYSA-N
• SMILES: COc1c(cc(cc1C(C)(C)C)P(Cl)c2cc(c(OC)c(c2)C(C)(C)C)C(C)(C)C)C(C)(C)C

Description and Uses

It is used as a reactant for asymmetric hydrogenation with iridium catalysts, chemo selective reaction with deprotonated 2-hydoxy-3,3,N-trimethylbutanamide. It is also used as a reactant for synthesis of phosphine- containing amino acids and peptide-based catalyst ligands, nonracemic phosphine-containing amino acids for palladium- catalyzed asymmetric allylic substitution reactions.

Safety

• Symbol(GHS): GHS02
• Signal word: Warning
• Hazard statements: H228
• Precautionary statements: P210
• PPE: Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
• Hazard Codes: F
• Risk Statements: 11
• RIDADR: UN3261
• WGK Germany: 3
• HazardClass: 8
• PackingGroup: II
• Storage Class: 4.1B - Flammable solid hazardous materials
• Hazard Classifications: Flam. Sol. 2